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This summer school provides participants with an overview of the most relevant experimental models and innovative tools for studying the complex pathophysiology of CKD progression. In parallel, the cellular and molecular bases of CKD progression will be presented. The school is being developed as part of the TrainCKDis network (Multidisciplinary Training in Chronic Kidney Disease: from genetic modifiers to drug discovery; www.trainckdis.eu): a European innovative, multidisciplinary, and intersectoral training programme to prepare the next generation of top-level scientists to develop creative solutions for transforming CKD research. The TrainCKDis project is funded under the Horizon 2020 Marie Skłodowska-Curie Action Innovative Training Network (H2020 MSCA-ITN-2019).